The Importance of Methylation
Key PointsRevolution Health and Wellness, What is Methylation and Why Should You Care?
• Methylation turns genes on and off.
• Methylation is fundamental to the control of healthy gene expression.
• This means methylation affects your DNA (genetic code).
• Your ability to detoxify is dependent upon your methylation pathway.
• Your ability to methylate helps to process toxins and hormones.
Methylation is the process of adding methyl groups — a chemical compound composed of one carbon and three hydrogen atoms — to a molecule. Methylation is a chemical reaction that occurs in every cell and tissue in your body. Enzymes, hormones, and genes are proteins and the process of methylation affects them all. Methylation can turn genes on or off, which can either be beneficial or harmful for your health, depending on the gene.
In many instances, methylation of proteins helps your body detoxify. For example, the methylation process helps convert the potentially toxic amino acid called homocysteine into a beneficial amino acid known as methionine.
Moreover, various nutrients dramatically affect methylation. Methyl donors (e.g., choline and supplements like organic sulfur) donate methyl groups to proteins, while methylating co-factors like zinc and vitamin B12 facilitate the process by monitoring specific methylation reactions. How well your body methylates is essential to your overall health. If there is a disruption in the methylate process, toxins can build up in your bloodstream and cause serious health concerns such as: heart attacks, strokes, dementia, depression, migraines, cancer, and birth defects.
Suzy Cohen summarizes the critical importance of methylataion in her article entitled, “Methylation Problems Lead to 100s of Diseases.”
Methylation defects reduce our ability from detoxifying properly, repairing the damage and fighting the infection and co-infections. This explains the severe symptoms that come and go in some people…Suzy Cohen, Methylation Problems Lead to 100s of Diseases.
Problems in the methylation pathway are not always genetic traits. In any case, it may cause a deficiency of methylfolate in your body, and thus a deficiency of glutathione, which leads to toxin build up in your bloodstream and tissues. Glutathione is known as the ‘master antioxidant’ of the body…
Because people with a methylation difficulty have trouble eliminating poisons, these build up in the body and that’s what contributes to many health concerns. Opening up the methylation road block helps clear your body of poisons and that should help reduce symptoms.
In the same report, Ms. Cohen adds that your ability to drive the methylation pathway is limited if you lack certain vitamins and minerals, such as: zinc, magnesium, riboflavin (vitamin B2), pyridoxine (vitamin B6), methylcobalamin (vitamin B12), and folate from food or folinic acid.